Evolution of the genomic landscape in NSCLC

Speaker: Keith Kerr

K. Kerr discusses the study of the whole-exome sequencing in NSCLC tumours. The findings demonstrate spatial and temporal heterogeneity of driver mutations and copy number events. The study is an attempt to address an unmet need to elicit the implications of intratumour heterogeneity for biomarker validation, therapeutic response and patients survival.

Discussion Points

  • Description of this study focusing on heterogeneity of NSCLC
  • What have we learned from the results?
  • How could this affect clinical practice in the future?

Abstract Discussed

LBA36 - Evolution of the genomic landscape in non-small cell lung cancer