ESMO Factsheets on Biomarkers

The ESMO Translational Research and Personalised Medicine Working Group has developed a number of factsheets of validated biomarkers designed to assist you in your daily practice. A biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. Biomarkers are key components of translational studies. Ideally, the development of targeted therapies should be closely coupled with the identification and validation of biomarkers.

In this section, you can find factsheets on biomarkers prepared by esteemed European experts with statements on:

  • Prognostic value
  • Predictive value
  • Testing recommendations
  • Ensuring quality and timely testing results
  • Patient selection

Watch Prof. Kerr explaining the pathologist's perspective

Read the article on immunology biomarkers by John Haanen


Topic Title Author
Breast Cancer ER in Breast Cancer Giuseppe Viale
Gastrointestinal Cancers - Colon Cancer - Rectal Cancer RAS in Colorectal Cancer Teresa Troiani
Gastrointestinal Cancers - Gastric Cancer HER2 in Gastric Cancer Giuseppe Viale
Lung and other Thoracic Tumours ALK in Lung Cancer Keith Kerr
Lung and other Thoracic Tumours EGFR in Lung Cancer Keith Kerr
Melanoma and other Skin Tumours BRAF in Melanoma Nicola Normanno
Melanoma and other Skin Tumours NRAS in Melanoma Nicola Normanno