Selected Treatment Schedules: Cholangiocarcinoma, Hepatocellular Carcinoma

Selected Treatment Schedules

2dd, twice daily; AUC, area under the concentration–time curve; BMI, body mass index; FU, fluorouracil; HER2, human epidermal growth factor receptor 2; FOLFIRI, folinic acid, fluorouracil and irinotecan; 5-FU, 5-fluorouracil.


(Neo)adjuvant Palliative
--- GemCis: 3-weekly gemcitabine 1000 mg/m2 d1 and 8, cisplatin 25 mg/m2 d1 and 8[32]


32. Valle J, Wasan H, Palmer DH, et al. Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer. N Engl J Med 2010; 362:1273–1281.

Hepatocellular carcinoma

(Neo)adjuvant Palliative
--- Sorafenib 2dd 400 mg[33]


33. Llovet JM, Ricci S, Mazzaferro V, et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008; 359:378–390.

Last update: 08 July 2016