Tumour Sites: Sarcomas

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J.M. Broto elaborates the results from an interim analysis of prospective, randomised study with neoadjuvant anthracycline/ifosfamide chemotherapy in localised high-risk adult soft tissue sarcomas (STS) of the extremities and trunk wall as presented at ESMO 2016. Neoadjuvant testing is on good direction to change the treatment paradigm in this setting. He digs also into perspective of other neoadjuvant approaches such as immunomodulation and modulation of tumour microenvironment.