29P - Association of polymorphisms in the microRNA target sites and survival of patients in early-stage non-small-cell lung cancer
|Date||28 March 2014|
|Session||Lunch and poster display session|
|Topics|| Non-Small-Cell Lung Cancer, Early Stage
|Presenter||Jin Eun Choi|
|Citation||Journal of Thoracic Oncology (2014) 9 (Supplement 9): S7-S52. 10.1097/JTO.0000000000000131|
J.E. Choi1, M.J. Hong1, J. Jang1, H. Jeon1, Y.Y. Choi1, J.Y. Park2
MicroRNAs (miRNAs) have a key role in carcinogenesis through the negative regulation of their target genes. This study was conducted to investigate the associations between single-nucleotide polymorphisms (SNP) located in the microRNA target sites (poly-miRTSs) and survival of patients with early-stage non–small cell lung cancer (NSCLC), and to identify the lung cancer prognosis-specific poly-miRTS.