29P - Association of polymorphisms in the microRNA target sites and survival of patients in early-stage non-small-cell lung cancer

Date 28 March 2014
Event ELCC 2014
Session Lunch and poster display session
Topics Non-Small-Cell Lung Cancer, Early Stage
Translational Research
Presenter Jin Eun Choi
Citation Journal of Thoracic Oncology (2014) 9 (Supplement 9): S7-S52. 10.1097/JTO.0000000000000131
Authors J.E. Choi1, M.J. Hong1, J. Jang1, H. Jeon1, Y.Y. Choi1, J.Y. Park2
  • 1Department Of Biochemistry And Cell Biology, School Of Medicine, Kyungpook National University, 700-422 - Daegu/KR
  • 2Internal Medicine, Kyungpook National University School of Medicine, 702-210 - Daegu/KR

Abstract

MicroRNAs (miRNAs) have a key role in carcinogenesis through the negative regulation of their target genes. This study was conducted to investigate the associations between single-nucleotide polymorphisms (SNP) located in the microRNA target sites (poly-miRTSs) and survival of patients with early-stage non–small cell lung cancer (NSCLC), and to identify the lung cancer prognosis-specific poly-miRTS.