79P - Role of expression levels of FABP3, H19, TFPI2, ARK1B1 CYP3A5, SCGB3A2 genes in adenocarcinoma stage I patients.

Date 28 March 2014
Event ELCC 2014
Session Lunch and poster display session
Topics Non-Small-Cell Lung Cancer, Early Stage
Pathology/Molecular Biology
Presenter Lucio Crinò
Citation Journal of Thoracic Oncology (2014) 9 (Supplement 9): S7-S52. 10.1097/JTO.0000000000000131
Authors L. Crinò1, V. Ludovini1, A. Siggillino1, F. Bianconi2, F.R. Tofanetti1, L. Pistola1, G. Metro1, M. Ragusa3, A. Sidoni4, F. Puma3
  • 1Medical Oncology Division, Ospedale S. Maria della Misericordia, 06156 - Perugia/IT
  • 2Department Of Electronic And Information Engineering, Perugia University, 06132 - Perugia/IT
  • 3Department Of Thoracic Surgery, University of Perugia, Perugia/IT
  • 4Institute Of Pathological Anatomy And Histology, University of Perugia, Perugia/IT

Abstract

Background:In a previous study, we compared gene expression profiling from adenocarcinoma (ADC) specimens and normal lung (NL) tissue with non relapse (NR) and early relapse (ER), and we selected 5 genes up-regulated and 4 genes down-regulated were predictive for clustering patients (pts) (Siggillino et al. ECCO 2011). Here, we validate our results using an independent cohort of patients with lung ADC stage I