73P - Investigating neuroendocrine markers of small cell lung cancer
|Date||28 March 2014|
|Session||Lunch and poster display session|
|Topics|| Small-Cell Lung Cancer
|Citation||Journal of Thoracic Oncology (2014) 9 (Supplement 9): S7-S52. 10.1097/JTO.0000000000000131|
T. Layton1, A. White2, S. Meredith2
Small cell lung cancer (SCLC) is a widespread and devastating disease. SCLC tumours contain a neuroendocrine cell population that exhibit ectopic hormone production in a minority of patients. The aim of this study was to investigate a panel of neuroendocrine peptides as potential biomarkers fof SCLC, including pro-opiomelanocortin, neuron specific enolase, chromogranin A and neural-cell adhesion molecule. This study validates further investigation into the neuroendocrine phenotype in SCLC, and POMC as a potential biomarker for the disease.