6P - Estrogen receptor beta over expression in women with lung adenocarcinoma is associated with better survival

Date 28 March 2014
Event ELCC 2014
Session Lunch and poster display session
Topics Lung and other Thoracic Tumours
Pathology/Molecular Biology
Presenter Nensi Lalic
Citation Journal of Thoracic Oncology (2014) 9 (Supplement 9): S7-S52. 10.1097/JTO.0000000000000131
Authors N.J. Lalic
  • Invasive Diagnostic Procedures, Institute of Oncology Vojvodina, 21204 - Sremska Kamenica/YU

Abstract

Adenocarcinoma of lung is becoming the most common histologic type of lung cancer in both sexes. It is more frequent in females than in males and developes more frequently than other histologic types in individuals who have never smoked. This evidence suggests that other etilogic factors of lung cancer need to be ivestigated, such as sex hormones. Recent studies have shown that estrogens promote the growth of lung cancer cells and may potentially be responsible for incresed susceptibility to lung cancer in woman. The aim of this study was to elucidate the correlation between expression of beta estrogen receptor and clinicopathologic factors and prognosis in adenocarcinoma of the lung.