151P - Post-treatment effects of lung cancer on spinal fracture

Date 17 April 2015
Event ELCC 2015
Session Poster lunch
Topics Supportive Care
Non-Small-Cell Lung Cancer, Metastatic
Presenter Malcolm Tagbarha
Citation Annals of Oncology (2015) 26 (suppl_1): 45-47. 10.1093/annonc/mdv051
Authors M.O. Tagbarha
  • Public Health, University of Abuja, 100009 - Abuja/NG

Abstract

Aim/Background

To ascertain whether lung cancer increases the risk for spinal fractures during and after treatment.

Methods

The medical records of more than 100 lung cancer survivors were assessed from six Teaching Hospitals in Eastern (Ethiopia and Tanzania) and Southern African countries from 2003-2013. We checked for osteolytic lesions and osteoblastic lesion as the patients have undergone several kinds of screening during and after cancer treatment including DXA (Dual-energy X-ray Absorptiometry), plain X-ray or magnetic resonance imaging (MRI) to screen for metastatic bone disease.

Results

We found that an estimated 30-40% of the lung cancer patients developed bone metastases and disrupted the balance between bone breakdown and repair which caused reduction of bone in some areas and increased density in others. As a result, the bone was weakened and became more prone to spinal fracture after treatment.

Conclusions

As lung cancer has spread thereby causing spinal fractures, treatment needs to be focused on disease control with chemotherapy. The treatment of bone metastases will be primarily dependent on an effective treatment against lung cancer itself.

Disclosure

The author has declared no conflicts of interest.