1631 - Phyisical and emotional symptoms in patients with solid and haematologic malignancies without metastases, on cure or follow-up: are they overlapping?

Date 28 September 2012
Event ESMO Congress 2012
Session Publication Only
Topics Haematologic Malignancies
Palliative and Supportive Care
Presenter Carla Ripamonti
Authors C.I. Ripamonti1, M.A. Pessi2, A. Maruelli3, S. Boldini4, G. Miccinesi5, E. Bandieri6, L. Buonaccorso7
  • 1Supportive Care In Cancer Unit, Hematologic And Pediatric Onco-hematologic Department, Fondazione IRCCS - Istituto Nazionale dei Tumori, 20133 - Milano/IT
  • 2Supportive Care In Cancer, Fondazione IRCCS, Istituto Nazionale Tumori, 20133 - Milano/IT
  • 3Psychology Unit, LILT and Centre for Oncological Rehabilitation CERION of Florence, 50100 - Firenze/IT
  • 4Supportive Care In Cancer,, Fondazione IRCCS, Istituto Nazionale dei Tumori Milano, 20133 - Milano/IT
  • 5Epidemiology, Cancer Prevention and Research Institute ISPO Florence, 50141 - Florence/IT
  • 6Oncological Unit, Azienda USL Modena CeVEAS Modena, 41137 - Mirandola Modena/IT
  • 7Psychology, AMO Association of Oncological Patients from nine towns and villages in the Northen Area of Modena, 41137 - Mirandola (modena)/IT

Abstract

In a prospective study carried out on 88 patients with solid cancer on cure and 20 on follow up (Group A) and 86 patients with haematologic malignancies (68 on cure) (Group B), we assessed the presence and intensity of physical and emotional symptoms through the Edmonton Symptom Assessment Scale (ESAS). In both groups, whereas no correlation was observed between age or religiousness and ESAS symptoms, a score above the clinical cut off for HADS (10/11) was associated with higher intensity of almost all symptoms. Drowsiness was less reported by patients with HADS <10 (p = 0.005). In respect to Group A, where a significant association was observed, in Group B uncontrolled pain was not correlated with HADS score above the cut off. Being on cure (rather than in follow up) was associated with dyspnoea for group B only. Uncontrolled pain and drowsiness (score ≥5; p = 0.054 and p = 0.013 respectively) were reported more often in patients with KPS 70-90 vs those with KPS > 90 for group A only. Whereas, for group B the associations with low KPS were for uncontrolled anorexia, not-well being and dyspnoea (p = 0.002; p = 0.029; p = 0.018 respectively). In both groups patients with higher proportion of uncontrolled depression or drowsiness were significantly associated to receiving psychological support. Pain, anxiety and not-well being were correlated with psychological support for group A only. We believe that the routinary assessment of physical and emotional symptom in patients with both malignancies is mandatory to recognize all the symptoms with a particular attention to the emotional ones.

Phyisical and emotional symptoms in patients with solid and haematologic malignancies without metastases, on cure or follow-up: are they overlapping?

Disclosure

All authors have declared no conflicts of interest.