174P - Mesenchymal tumors of the mediastinum and the role of surgery in their treatment

Date 17 April 2015
Event ELCC 2015
Session Poster lunch
Topics Lung and other Thoracic Tumours
Surgery and/or Radiotherapy of Cancer
Presenter Fatmir Caushi
Citation Annals of Oncology (2015) 26 (suppl_1): 51-54. 10.1093/annonc/mdv053
Authors F. Caushi1, H. Hafizi2, A. Mezini2, I. Skenduli1, D. Xhemalaj3
  • 1Thoracic Surgery, University Hospital of Lung Disease "Shefqet Ndroqi", 12345 - Tirana/AL
  • 2Pneumology, University Hospital of Lung Disease "Shefqet Ndroqi", Tirana/AL
  • 3Pathologic Anatomy, University Hospital of Lung Disease "Shefqet Ndroqi", Tirana/AL

Abstract

Aim/Background

Mediastinal mesenchymal lesions are rare tumors that are composed of two or more different histological mesenchymal elements. 6% to 8% of all mediastinal lesions are primary mesenchymal tumors. 55% of mediastinal mesenchymal tumors are malignant. In order to assess the role of surgery in their treatment, we have undertaken this study.

Methods

This is a retrospective study based in a ten year single clinic experience. The period of follow-up for the patients that have been operated was approximately three years.

Results

Mesenchimal tumors of the mediastinum constitute 13,6% of all mediastinal lesions that have been treated in or clinic, meanwhile 50% of this tumors were benign lesions and the rest malignant. All of them have undergone surgical treatment, where the radical extirpation of the tumor was possible in 83,4% of cases. All patients with malignant lesions after the surgery were treated by radiotherapy. 16,6% of cases had recurrences and no case of death was reported during and immediately after the surgery.

Conclusions

Because mediastinal mesenchymal tumors can reach impressively large sizes before detection, they typically present with symptoms such as dyspnea, cough and chest pain. The higher incidence of cases in our study compared with the others is thought because of the recently boom of our radiology. Although they are a mix of histological types where nearly half of them are tumors of endothelium, the role of surgery even for cytoreduction in few cases (16,6%) was effective for their treatment. Multimodal treatment of malignant lesions is advisable.

Disclosure

All authors have declared no conflicts of interest.