51P - Generation of immunogenic killed tumor cells for dendritic cell-based lung cancer immunotherapy

Date 28 March 2014
Event ELCC 2014
Session Lunch and poster display session
Topics Cancer Immunology and Immunotherapy
Lung and other Thoracic Tumours
Translational Research
Presenter Irena Adkins
Citation Journal of Thoracic Oncology (2014) 9 (Supplement 9): S7-S52. 10.1097/JTO.0000000000000131
Authors I. Adkins, N. Hradilova, L. Sadilkova, I. Truxova, I. Vancurova, L. Sojka, J. Palich Fucikova, R. Spisek
  • Research Department, Sotio a.s., 17000 - Prague/CZ


High hydrostatic pressure (HHP) was shown to induce immunogenic tumor cell death, which is now believed to be crucial for an effective anti-tumor response. HHP as a physical cell-inducing modality can be suitable for the preparation of immunotherapeutic cancer vaccines