7P - Exploring tumor-stroma interaction in lung adenocarcinomas: a genome wide analysis of the response to BMP signaling in human lung fibroblasts
|Date||28 March 2014|
|Session||Lunch and poster display session|
|Topics|| Lung and other Thoracic Tumours
|Citation||Journal of Thoracic Oncology (2014) 9 (Supplement 9): S7-S52. 10.1097/JTO.0000000000000131|
M. Rajski1, M. Buess2
The BMP signaling system plays a key role in development, morphogenesis and cancer. As observed for development, heterotypic cellular interactions also play an essential role in carcinogenesis. The aim of this study was to characterize the response of lung stromal fibroblasts to BMPs and their antagonists and investigate its potential role in human lung adenocarcinomas.