23P - Establishment of lung cancer mouse model induced by benzo (a) pyrene

Date 28 March 2014
Event ELCC 2014
Session Lunch and poster display session
Topics Basic Science
Lung and other Thoracic Tumours
Presenter Hwa Sik Moon
Citation Journal of Thoracic Oncology (2014) 9 (Supplement 9): S7-S52. 10.1097/JTO.0000000000000131
Authors H.S. Moon1, H.Y. Lee2, I.K. Kim1, C.D. Yeo2, C.H. Kim2, S.H. Lee1
  • 1Department Of Internal Medicine, St. Paul’s Hospital, The Catholic University of Korea, 130-709 - Seoul/KR
  • 2Department Of Internal Medicine, The Catholic University of Korea, 130-709 - Seoul/KR

Abstract

Several novel animal models for lung cancer have been developed in recent years. Cancer mouse models by exposure to various carcinogens are still commonly used tumor mouse models. Benzo(a)pyrene (B[a]P) is one of the major environmental pollutants and induces carcinogenesis specifically targeting the lung. The aim of this study is to establish a standard design of mouse models for lung cancer following B[a]P exposure method.