Advances in Research of Gynaecological Malignancies: Focus on Ovarian and Endometrial Cancers

Speaker: Sandro Pignata

S. Pignata reviews results of studies on gynecological malignancies presented at ASCO 2015. He provides expert insights on the benefit of trebaninib in patients with ascites in the TRINOVA-1 study, Biomarker-driven PENELOPE study of pertuzumab in PT-resistant ovarian cancer, toxicity data in the PORTEC-3 study, and risk of uterine cancer following salpingo-oophorectomy in women with BRCA mut.

Discussion Points

  • Recurrent ovarian cancer: Results from TRINOVA-1 study
  • Results from PENELOPE trial suggest further investigations
  • High-risk endometrial cancer: new insight into adjuvant chemotherapy
  • Preventive hysterectomy in BRCA+ women: a multicentre and prospective study