P-343 - Survival of patients with multiple colorectal cancer metastases to the liver after radiofrequency thermal ablation

Date 04 July 2015
Event WorldGI 2015
Session Posters
Topics Colon Cancer
Rectal Cancer
Surgery and/or Radiotherapy of Cancer
Presenter O. Kuznetsova
Citation Annals of Oncology (2015) 26 (suppl_4): 1-100. 10.1093/annonc/mdv233
Authors O. Kuznetsova, V. Dubinina, V. Maksymovskyi
  • Odessa National Medical University, Odessa/UA

Abstract

Introduction

The most important and objective characteristic of the method of treatment, the average duration of life of patients with commencement of the treatment or the average duration of remission of the disease.

Methods

We studied 33 patients with multiple metastatic lesions of the liver for colorectal cancer, which, because of the weight pantries poor pathology surgical treatment was contraindicated. In total were destroyed 87 of liver metastases with a diameter from 1.0 up to 3 cm in the greatest dimension and number of lesions from 3 to 5.

Results

The analysis of long-term survival of the tested patients showed the following: the survival of patients after radiofrequency thermal ablation in the five-year period had a characteristic dynamics. The value of a function of survival drops sharply during the first 10 months with the onset of the disease. Since 10 months, the function decreases less sharply. Therefore, the first 10 months after the onset of the disease are the most critical. The chance to live more than 6 months after the intervention exceeds 0,77, more than 24 months is 0.55. According to our records, 1 patient achieved a 4-year-old line life.

Conclusion

The above suggests that radiofrequency thermal ablation, not as an alternative to liver resection is an effective minimally invasive method of surgical treatment that allows with minimal complications and blood loss to achieve the expected positive results in the treatment of patients with metastatic colorectal cancer who are contraindicated for surgical treatment.