P-252 - The effectiveness of colonoscopy in early gastric cancer patients who received endoscopic submucosal dissection

Date 04 July 2015
Event WorldGI 2015
Session Posters
Topics Gastric Cancer
Imaging, Diagnosis and Staging
Presenter J.H. Jeon
Citation Annals of Oncology (2015) 26 (suppl_4): 1-100. 10.1093/annonc/mdv233
Authors J.H. Jeon, D.H. Kang, H.W. Kim, C.W. Choi, S.B. Park, S.J. Kim, D.G. Yu, W.C. Kim, H.S. Nam
  • Pusan National University Yangsan Hospital, Yangsan/KR

Abstract

Introduction

Aim of this study was to investigate the incidence of high risk colorectal neoplasm and colorectal cancer in patients who received endoscopic submucosal dissection compared with healthy controls.

And we assessed the need of surveillance colonoscopy in patients with early gastric cancer.

Methods

We investigated 205 patients with EGC who received ESD. 425 sex and age-matched patients without gastric neoplasm were included as a control group. All patients of two groups received surveillance colonoscopy before or after 6months from gastric ESD between January 2011 and December 2014.

Results

57/205 (26.4%) patients were diagnosed with high risk colorectal neoplasm in EGC group and 12/425 (2.8%) in controls (p < 0.01). 23/205 patients (11.2%) in EGC group were diagnosed with colorectal cancer and 6/425 (1.4%) in controls (p < 0.01). Univariate analysis showed that high risk colorectal neoplasm was related with presence of EGC, age, DM, and colorectal cancer was associated with presence of EGC, colorectal cancer family history. Multivariate analysis showed that EGC (OR 7.3, 95% CI 4.6-10), age (OR 6.1, 95% CI 3.4-8.8) were risk factors of high risk colorectal neoplasm. And presence of EGC (OR 6.39, 95% CI 2.78-10.0), age (OR 3.66, 95% CI 1.59-5.73), colorectal cancer family history (OR 3.24, 95% CI 1.83-4.65) were risk factors of colorectal cancer.

Conclusion

High risk colorectal neoplasm and colorectal cancer developed more frequently in EGC group who received gastric ESD than control group. So, we recommend a surveillance colonoscopy in patients with EGC who received gastric.