P-067 - Management of gastric indefinite neoplasia

Date 04 July 2015
Event WorldGI 2015
Session Posters
Topics Gastric Cancer
Presenter T.W. Lim
Citation Annals of Oncology (2015) 26 (suppl_4): 1-100. 10.1093/annonc/mdv233
Authors T.W. Lim, J.H. Kim, T.S. Kim, S.K. Oh, D.H. Kang, H.W. Kim, C.W. Choi, S.B. Park, S.J. Kim
  • Pusan National University Yangsan Hospital, Yangsan/KR

Abstract

Introduction

Clinical management of gastric indefinite neoplasia (category 2 lesion) from endoscopic forceps biopsy is difficult to decide management in some conditions such as suspicious of early gastric cancer (EGC), macroscopically.

Methods

This retrospective study enrolled 127 patients of gastric indefinite neoplasia on index forceps biopsy. We analyzed the initial endoscopic distinctive features of lesions and predictive factors of EGC.

Results

After complete work-up, the ultimate pathologic diagnoses were early gastric cancer (n =28, 22.0%), adenoma (n =9, 7.0%), and non-neoplasm (n =90, 70.8%). In the univariate analysis, lesion size more than 10 mm, surface nodularity and surface redness were associated risk factors. In the multivariate analysis, lesions diameter (p =0.023, OR 11.409, 95% CI 1.441-90.762) and surface redness (p =0.012, OR 3.762, 95% CI 1.312-10938) were significant risk factors.

Conclusion

Gastric indefinite neoplasia with larger size (≥ 10mm) and surface redness might be require more definite diagnostic modalities rather than simple and serial follow up endoscopy.

Table: P-067