178P - Survival patterns in colorectal cancer patients in the United States

Date 19 December 2015
Event ESMO Asia 2015 Congress
Session Poster presentation 1
Topics Colon Cancer
Rectal Cancer
Presenter Ahmed Meshref
Citation Annals of Oncology (2015) 26 (suppl_9): 42-70. 10.1093/annonc/mdv523
Authors A. Meshref1, M. Mousa2, K. Alsabahy1
  • 1Faculty Of Medicine, Suez Canal University, 41111 - Ismailia/EG
  • 2Faculty Of Medicine, Suez Canal University, Ismailia/EG

Abstract

Aim/Background

This study aimed at evaluation of different relative survival rates of patients with colorectal cancer.

Methods

The SEER database was used to gather patient information. All 18 SEER registries were used. Patients diagnosed from 1998 to 2007 were included in the analysis. Relative five-year survival rate was calculated & compared using the SEER*Stat software version 8.4.1. Data were extracted into IBM SPSS version 20 to generate Kaplan Meier curve for each age group.

Results

348707 patients in the SEER databases who met the selection criteria were divided into 5 age groups according to age of diagnosis. The results showed that the most affected age group was 60-79 years (49.98%). By comparing five-year relative survival rate of different therapeutic modalities the result showed that there was statistically significant difference between five-year relative survival rate of patient who had surgical intervention 71.7% (95% CI: 70.9-71.4) comparing with patient who received radiation therapy 62.4% (95% CI: 61.8-63). There was statistically significant difference between five-year relative survival rate in patient who had surgical intervention 71.7% (95% CI: 70.9-71.4) comparing with non operable patient who hadn't any surgical intervention 17% (95% CI: 16.5-17.4). Also there was statistically significant difference between five-year relative survival rate in patient who received radiation therapy 62.4% (95% CI: 61.8-3) comparing with patient who hadn't receive radiation therapy 64.4% (95% CI: 64.1-64.6). There was no statistically significant difference between relative survival rates according to gender and race.

Conclusions

The study showed that surgical intervention is the best in treatment of colorectal cancer in different age groups comparing with radiation therapy because it gives high five-year relative survival rate comparing with radiation therapy. Radiation therapy also has high five-year relative survival rate comparing with five-year relative survival rate in patient who didn't receive any therapeutic modalities for colorectal cancer.

Clinical trial identification

Disclosure

All authors have declared no conflicts of interest.