P-0160 - Gastrointestinal cancers: epidemiological, clinical, histological and therapeutic characteristic (210 cases treated in the radiotherapy department o...

Date 28 June 2014
Event World GI 2014
Session Poster Session
Topics Cancer Aetiology, Epidemiology, Prevention
Gastrointestinal Cancers
Surgery and/or Radiotherapy of Cancer
Presenter Zahra Farhane Fatima
Citation Annals of Oncology (2014) 25 (suppl_2): ii14-ii104. 10.1093/annonc/mdu165
Authors Z. Farhane Fatima1, K. Loikili2, Z. Alami3, O. Masbah3, T. Bouhafa3, A. Elmazghi3, K. Hassouni3
  • 1Radiotherapy Department, University Hospital of Hassan II, Fes/MA
  • 2University Hospital of Hassan II, Fes/MA
  • 3Radiotherapy Department University Hospital of Hassan II, Fes/MA

Abstract

Introduction

Gastrointestinal cancers represent an important public health problem in Morocco by their frequency and severity. The objective of this work is to describe the epidemiological, histological, clinical and therapeutic characteristic.

Methods

This is a retrospective study spread over 2 years (from 1 January 2012 to 31 December 2013), on all patients treated for gastrointestinal cancer who underwent radiotherapy in the department of radiotherapy in the university hospital of Hassan II- FES.

Results

Gastrointestinal cancers accounted for 12% of cancers treated in our department during the period of 2 years. The average age is 55 years, sex ratio is 1,5 (126 F/84M). - 78% are rectal. The average age is 45 years. The sex ratio is 1,8 (F/M). Rectal syndrome is the main reason for consultation. The average time to diagnosis is 8 months. The lower rectum is achieved in 42% of cases. The most common histological type is adenocarcinoma. Therapeutically 25% of patients underwent a preoperative concomitant radiochemotherapy, 65% received external radiotherapy and 10% received postoperative radiotherapy. - 7% of cancers are anal. The average age is 58 years. The sex ratio is 1,2 (F/M). Anal bleeding is the main reason for consultation. The average time to diagnosis is 4 months. The most common histological type is squamous carcinoma. Therapeutically All patients underwent a concomitant radiochemotherapy - 5% are gastric cancers. The average age is 51 years. The sex ratio is 1,5 (F/M). Epigastric pain is the main reason for consultation. The average time to diagnosis is 8 months. The most common histological type is Adenocarcinoma. Therapeutically All patients underwent a postoperative concomitant radiochemotherapy. - 9% are esophageal. The average age is 47 years. The sex ratio is 1,6 (F/M). Dysphagia is the main reason for consultation. The average time to diagnosis is 4 months. The most common histological type is squamous carcinoma. Therapeutically All patients underwent concomitant radiochemotherapy.

Conclusion

The severity of gastrointestinal cancers is mainly due to the delay in diagnosis. Radiotherapy plays an important role in the treatment of this cancers. The concomitant radiochemotherapy has increasingly a place in the armamentarium of these cancers and has proven results in terms of local control and survival.