P-0073 - Comparison of the average body weight and waist circumference in patient with Barrett's oesophagus and patient without lesions
|Date||28 June 2014|
|Event||World GI 2014|
|Topics|| Oesophageal Cancer
Cancer Aetiology, Epidemiology, Prevention
|Citation||Annals of Oncology (2014) 25 (suppl_2): ii14-ii104. 10.1093/annonc/mdu165|
Barrett's oesophagus is defined as changes in the mucosa of the lower esophagus, in the form of outbreaks of intestinal metaplasia, increasing the risk of developing cancer of the esophagus. In the last few years have seen a significant growth the incidence of esophageal cancer in many developed countries. Excess body weight is believed to be one of the factors responsible for an increase in the incidence of oesophageal cancer in highly developed countries. The aim of this work was to compare the mean body weight and waist circumference between patients with precancerous lesions in the oesophagus (Barrett's oesophagus) and those without any lesions.
The study was conducted in outpatients directed to the gastroscopy because of dyspeptic symptoms. The eligibility criteria for the study: people diagnosed with Barrett's esophagus based on endoscopic examination, histopathology confirmed by the result of clippings; people without morphological and pathological changes in the esophagus (the norm). The study included 79 people who fulfilled the above criteria. Two groups were extracted: group 1 – people with diagnosed of Barrett's esophagus (41 patients) and group 2 – those with no morphological and pathological changes of the esophagus (38 patients). The study consisted of anthropometric measurements (height, weight, BMI, waist circumference).
Average body weight and waist circumference in group 1 were higher compared to the values in group 2 - respectively, body weight: 75.5 ± 14.3 kg vs. 73.3 ± 12.3 kg (p = 0,64; α = 0,05); men 77.7 ± 8.9 vs.79.3 ± 15.3 kg (p = 0,68; α = 0,05); women 69.5 ± 10.3 vs. 69.7 ± 13.7 kg (p = 0,96; α = 0,05) and waist circumference 89.5 ± 11 cm vs. 86.3 ± 12.50 cm (p = 0,25; α = 0,05); men 91.5 ± 11.4 vs. 89.4 ± 6.8 cm (p = 0,68; α = 0,05); women 84.1 ± 15.1 vs. 85.66 ± 9.32 cm (p = 0,72; α = 0,05). Also, a slightly higher BMI was observed in patients with Barrett's esophageal compared with the norm – BMI 25.9 ± 3.4 kg/m2 in group 1 vs. 25.5 ± 3.8 kg/m2 in group 2 (p = 0,61; α = 0,05); men 25.9 ± 3.7 vs.25.4 ± 2.5 kg/m2 (p = 0,79; α = 0,05); women 25.9 ± 3.2 vs. 25.6 ± 4.6 kg/m2 (p = 0,56; α = 0,05).
Statistical analysis of the data showed no significance in comparison of the average body weight and waist circumference in patient with Barrett's oesophagus and patient without lesions.