P-009 - Clinicopathological and epidemiological features of gastric cancer in young patients at Instituto Nacional de Enfermedades Neoplasicas Lima-Perú

Date 04 July 2015
Event WorldGI 2015
Session Posters
Topics Cancer in Young Adults
Gastric Cancer
Cancer Aetiology, Epidemiology, Prevention
Presenter C. Pacheco
Citation Annals of Oncology (2015) 26 (suppl_4): 1-100. 10.1093/annonc/mdv233
Authors C. Pacheco1, D. Enriquez1, E. Poquioma1, P. Montenegro2
  • 1Instituto Nacional de Enfermedades Neoplasicas, Lima/PE
  • 2Instituto Nacional de Enfermedades Neoplásicas (INEN), Lima/PE

Abstract

Introduction

Gastric cancer is one of the most common cancers, actually the second in incidence, little higher in men. Usually is higher in people over 40 years old. This study was designed to evaluate and compare the features of gastric cancer in young patients less than 40 years old with patients over 40 years old.

Methods

Medical records of 585 patients with gastric cancer, who received any kind of treatment, even surgery, chemotherapy or both at the Instituto Nacional de Enfermedades Neoplásicas Lima-Perú, between January 2010 and December 2012 were reviewed. They were divided into two groups young (≤40 yr, n = 69) and older patient (>40yr, n = 516).

Results

Advanced diseases (80% and 75%) and node metastasis (74.3% and 66%) were more common in both groups. In the Lauren classification, the diffuse type (54.2% and 16.9%, p: 0.001) was more common in young patients; the intestinal type (14.3% and 52.6%, p: 0.001) was more common in older patients. The 2 yr and 5 yr overall survival (38.2% - 31.6% and 58.3% and 49.6%, p: 0.001) was higher in older patients with a media of 80.2 months of survival. Young patients who received adjuvant chemotherapy went worse than older (media of survival 23.1m vs 33.9m, p: 0.001).

Conclusion

As conclusion, the gastric cancer is less common in young patients, the diffuse type is more common in this group of patients and they had less overall survival in comparison with older patients.