P-0070 - Clinico-epidemiological and therapeutic profile of gastric cancer: Experience of oncology department of regional military hospital of Oran

Date 28 June 2014
Event World GI 2014
Session Poster Session
Topics Gastric Cancer
Cancer Aetiology, Epidemiology, Prevention
Presenter Zohra Boudinar Fatema
Citation Annals of Oncology (2014) 25 (suppl_2): ii14-ii104. 10.1093/annonc/mdu165
Authors Z. Boudinar Fatema1, A. Boukerche2
  • 1Hemato-oncology Department, HMRU Oran, Oran/DZ
  • 2Department of Radiation Oncology, CHU Oran, Faculty of Medicine, University of Oran, Oran/DZ

Abstract

Introduction

The aim of our study was to analyze the clinico-epidemiological and therapeutic characteristics of gastric cancer in a cohort of patients treated in our department.

Methods

Retrospective study about a cohort of 63 cases of gastric cancer (40 adenocarcinoma, 18 Lymphoma and 4 GIST) admitted to the medical oncology department (regional military hospital of Oran) between January 2011 and June 2013.

Results

In a group of gastric adenocarcinoma, the mean age was 61 years (range 22-80). The tumors were metastatic in 82% of cases, 10% in locally advanced and localized in 8%. Surgical treatment affected only 7,5% of cases followed by adjuvant chemotherapy. A palliative chemotherapy was decided in 70% of cases and 22,5% of patients received a palliative care only. 40% died of their disease, 42,5% were lost of view and 7 patients (17,5) were still alive at the point date. In a group of lymphoma, the mean age was 62 years (range 24-85). All patients received RCHOP or CHOP with surgery to 3 cases. The complete response was observed in 44% of cases and overall survival at 3 years was 39%. In a group of GIST, the mean age was 55 years (range 27-73). All tumors were T4 and N+ and received Imatinib therapy (median number of cycles: 12). The disease was stable for all cases.

Conclusion

The gastric cancer was diagnosed at locally advanced stage which explains the poor prognosis of these cancers. A greater understanding of molecular changes associated with gastric cancer is needed to guide surgical and medical therapy.