P-0070 - Clinico-epidemiological and therapeutic profile of gastric cancer: Experience of oncology department of regional military hospital of Oran
|Date||28 June 2014|
|Event||World GI 2014|
|Topics|| Gastric Cancer
Cancer Aetiology, Epidemiology, Prevention
|Presenter||Zohra Boudinar Fatema|
|Citation||Annals of Oncology (2014) 25 (suppl_2): ii14-ii104. 10.1093/annonc/mdu165|
Z. Boudinar Fatema1, A. Boukerche2
The aim of our study was to analyze the clinico-epidemiological and therapeutic characteristics of gastric cancer in a cohort of patients treated in our department.
Retrospective study about a cohort of 63 cases of gastric cancer (40 adenocarcinoma, 18 Lymphoma and 4 GIST) admitted to the medical oncology department (regional military hospital of Oran) between January 2011 and June 2013.
In a group of gastric adenocarcinoma, the mean age was 61 years (range 22-80). The tumors were metastatic in 82% of cases, 10% in locally advanced and localized in 8%. Surgical treatment affected only 7,5% of cases followed by adjuvant chemotherapy. A palliative chemotherapy was decided in 70% of cases and 22,5% of patients received a palliative care only. 40% died of their disease, 42,5% were lost of view and 7 patients (17,5) were still alive at the point date. In a group of lymphoma, the mean age was 62 years (range 24-85). All patients received RCHOP or CHOP with surgery to 3 cases. The complete response was observed in 44% of cases and overall survival at 3 years was 39%. In a group of GIST, the mean age was 55 years (range 27-73). All tumors were T4 and N+ and received Imatinib therapy (median number of cycles: 12). The disease was stable for all cases.
The gastric cancer was diagnosed at locally advanced stage which explains the poor prognosis of these cancers. A greater understanding of molecular changes associated with gastric cancer is needed to guide surgical and medical therapy.