8P - Axillary sentinel lymph node biopsy: is it indicated in patients with microinvasive breast cancer?

Date 08 May 2014
Event IMPAKT 2014
Session Welcome reception and Poster Walk
Topics Breast Cancer
Imaging, Diagnosis and Staging
Presenter BeomSeok Ko
Citation Annals of Oncology (2014) 25 (suppl_1): i3-i3. 10.1093/annonc/mdu063
Authors B. Ko, H.J. Kim, J.H. Yu, J.W. Lee, B.H. Son, S.H. Ahn
  • General Surgery, Asan Medical Center, 138-736 - Seoul/KR



The role of axillary staging and natural history in microinvasive breast cancer (MIC) is not well known. This study assesses outcome in patients with ductal carcinoma in situ (DCIS) with microinvasion who did not undergo sentinel lymph node biopsy (SNB).


A retrospective analysis of DCIS with microinvasion (DCISM) patients surgically treated at the Asan Medical Center from March, 2003 to December, 2009 was conducted. Bilateral breast cancer patients and patients who underwent node dissection were excluded from the study. SNB was performed in most of DCIS patients after surgery when microinvasion was found, but in some patients with clinically negative axillary lymph node metastasis, SNB was omitted.


A total of 185 consecutive patients with DCISM were identified. Thirty-three patients did not undergo SNB [SNB(-) group], while 152 patients did [SNB(+) group]. No recurrence occurred in the SNB(-) group during a median follow-up period of 63.5 months, while one regional recurrence occurred in the SNB(+) group during a median follow-up period of 78.1 months. Distant recurrence was not found in two groups.


DCISM with clinically negative metastatic axillary lymph nodes is associated with a low risk of regional recurrence. Selective SNB should be considered for microinvasive breast cancer patients.


All authors have declared no conflicts of interest.