8P - Axillary sentinel lymph node biopsy: is it indicated in patients with microinvasive breast cancer?
|Date||08 May 2014|
|Session||Welcome reception and Poster Walk|
|Topics|| Breast Cancer
Imaging, Diagnosis and Staging
|Citation||Annals of Oncology (2014) 25 (suppl_1): i3-i3. 10.1093/annonc/mdu063|
B. Ko, H.J. Kim, J.H. Yu, J.W. Lee, B.H. Son, S.H. Ahn
The role of axillary staging and natural history in microinvasive breast cancer (MIC) is not well known. This study assesses outcome in patients with ductal carcinoma in situ (DCIS) with microinvasion who did not undergo sentinel lymph node biopsy (SNB).
A retrospective analysis of DCIS with microinvasion (DCISM) patients surgically treated at the Asan Medical Center from March, 2003 to December, 2009 was conducted. Bilateral breast cancer patients and patients who underwent node dissection were excluded from the study. SNB was performed in most of DCIS patients after surgery when microinvasion was found, but in some patients with clinically negative axillary lymph node metastasis, SNB was omitted.
A total of 185 consecutive patients with DCISM were identified. Thirty-three patients did not undergo SNB [SNB(-) group], while 152 patients did [SNB(+) group]. No recurrence occurred in the SNB(-) group during a median follow-up period of 63.5 months, while one regional recurrence occurred in the SNB(+) group during a median follow-up period of 78.1 months. Distant recurrence was not found in two groups.
DCISM with clinically negative metastatic axillary lymph nodes is associated with a low risk of regional recurrence. Selective SNB should be considered for microinvasive breast cancer patients.
All authors have declared no conflicts of interest.