ESMO Clinical Trials Tips and Tricks

Practical tips to assist you in your day-to-day clinical trial research

Developed by the ESMO Faculty on Principles of Clinical Trials and Systemic Therapy, the short presentations below aim to assist you in defining, running and reporting your clinical trial.

Principles of Clinical Trials and Systemic Therapy - ESMO Congress 2016

Introduction - Christian Dittrich

Under-reporting of harm in clinical trials - Alberto Ocana Fernandez

Unplanned versus pre-specified subgroup analysis reporting - Doug Altman

Quality of meta-analyses and why they sometimes lead to different conclusions - Jean-Pierre Pignon

Early reporting of efficacy endpoints and its potential impact: Biostatistical part - Jan Bogaerts

Early reporting of efficacy endpoints and its potential impact: Clinical part - Fatima Cardoso

Conclusions - Denis Lacombe

Defining your clinical trial

Pharmacological aspects of clinical trials – Alex Adjei, Emiliano Calvo, Anita Margulies, Josep Tabernero, Ian Tannock

Drugs development methodology: the unavoidable break with the past – Ahmad Awada, Nuria Kotecki, Alex Adjei, Guillem Argiles, Dirk Arnold, Jean-Yves Blay, Olivier Collignon, Christian Dittrich, Felip Janku, Denis Lacombe, Nicolas Penel, Josep Tabernero

Lessons learnt from the development of cytotoxics and perspectives - Nicolas Penel, Yazid Belkacemi, Emiliano Calvo, Fatima Cardoso, Christian Dittrich, Stefan Sleijfer

Overview of drug development and types of clinical trials - Denis Lacombe, Anita Margulies, Jan Tannock, Jan Bogaerts and Christian Dittrich

What to consider when deciding to participate in a trial as an investigator - Jean-Yves Blay and Emiliano Calvo

Pathological Aspects of Clinical Trial - Christoph Röcken

What to consider when designing a trial - Ulrich Keilholz, Dirk Arnold, Susen Burock, Emiliano Calvo, Urania Dafni, Nadia Harbeck, Eric Raymond, Piotr Rutkowski, Marcel Verheij

Innovative clinical trial designs in the era of precision oncology - Ahmad Awada, Hampig Raphael Kourie, Jean-Yves Blay, Nadia Harbeck, Paul Morten Mau-Sørensen, Stefan Sleijfer

Running your clinical trial

Clinical trial endpoints - Ian Tannock, Steinar Aamdal, Dirk Arnold, Urania Dafni, Ulrich Keilholz, Paul Morten Mau-Sørensen, Piotr Rutkowski, and Stefan Sleijfer

Informed consent - Thomas Cerny,  Jan Geissler, and Marie-Christine Hollerith

PRO assessment in cancer trials - Emiliano Calvo, Anita Margulies, Eric Raymond, Ian Tannock, Nadia Harbeck and Lonnekevan de Poll-Franse

Reporting and interpreting results

Understanding clinical trials statistics - Urania Dafni, Xanthi Pedeli, and Zoi Tsourti

Interpretation of Clinical Trials - Alberto Sobrero

Reporting side effects of therapy from early and pivotal clinical trials and definition of recommended doses - Ahmad Awada, Hampig Raphael Kourie, Christian Dittrich

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