Towards a Classification of Wild-Type GIST

  • Date: 10 Mar 2014
  • Topic: GIST

Speaker: Eva Wardelmann

E.Wardelmann discusses immunohistochemical and mutational classification of GIST; mutations known as "Wild-type GIST"; progressively increased understanding of rare Mutations and selection of the most appropriate therapy.

Discussion Points:

Gastrointestinal stromal tumours: an important evolution from a frequently mis-diagnosed disease to immuno-histochemical and mutational classification.

  • What mutations are characterised by the term “Wild-type GIST”?
  • What role does the identification of specific subtypes have in the selection of the most appropriate therapy?
  • Considering the progressively increased understanding of rare Mutations, can we expect further future changes in the definition of wild-type GIST?