P-068 - Prognostic factors related to clinical outcomes by self-expandable metal stent due to Malignant Gastric Outlet Obstruction

Date 04 July 2015
Event WorldGI 2015
Session Posters
Topics Gastric Cancer
Palliative Care
Surgery and/or Radiotherapy of Cancer
Presenter D.I. Jeong
Citation Annals of Oncology (2015) 26 (suppl_4): 1-100. 10.1093/annonc/mdv233
Authors D.I. Jeong, Y.Y. Choi, J.H. Kim, D.H. Kang, H.W. Kim, C.W. Choi, S.B. Park, S.J. Kim, D.G. Yu
  • Pusan National University Yangsan Hospital, Yangsan/KR

Abstract

Introduction

In patients with gastric outlet obstruction (GOO), There are significant differences between procedural success and clinical outcomes in Self-expandable metallic stent (SEMS). We investigated the prognostic factors associated with clinical outcomes of SEMS.

Methods

We retrospectively reviewed medical records of 118 patients who underwent the endoscopic SEMS placement due to malignant GOO from January 2010 to May 2014 Pusan national university Yangsan Hospital. We investigated the change in the Gastric Outlet Obstruction Scoring System (GOOSS) before and after procedure. Then we analyzed some prognostic factors associated with the improvement of GOOSS.

Results

our procedural success rate was 95% (112/118) and a clinical success rate was 82.1% (92/112). We defined clinical success as the improvement of GOOSS within 7days after stent placement. The lesion causing obstruction were stomach cancer 30 (32.6%), pancreatic cancer 28 (30.4%), cholangiocarcinoma 14 (15.2%), ampulla of vater cancer 7 (7.6%), gall bladder cancer 13 (14.1%). We analyzed variables associated with improvement of GOOSS and we identified some factors such as ECOG3 (Adjusted OR 10.5, p = 0.001, gall bladder cancer (Adjusted OR 9.235, p = 0.015), carcinomatosis peritonei (Adjusted OR 33.71, p0.001), impossibility of passing the endoscope through obstructive site (Adjusted OR 6.935, p = 0.039).

Conclusion

We found out some prognostic factors for Clinical outcomes by SEMS in malignant GOO. Physicians should take into account the effect of SEMS for patients with these factors.