P-0281 - Rectal cancer in the Algerian West: Clinical Aspects, Management and Outcomes of a cohort of 85 patients treated at the department of radiation onco...

Date 28 June 2014
Event World GI 2014
Session Poster Session
Topics Rectal Cancer
Surgery and/or Radiotherapy of Cancer
Presenter Abdelbaki Boukerche
Citation Annals of Oncology (2014) 25 (suppl_2): ii14-ii104. 10.1093/annonc/mdu165
Authors A. Boukerche1, A. Yahia2, A. Safir3, S. Hakem4, A. Dali-Youcef5
  • 1Department Of Radiation Oncology, CHU Oran, Faculty of Medicine, University of Oran, Oran/DZ
  • 2Department of radiation Oncology, CHUOran, Oran/DZ
  • 3Department of Hepato-Gastro-Enterology, CHUOran, Oran/DZ
  • 4Department of Hepato-Gasro-Enterology, CHUOran, Oran/DZ
  • 5Department of Radiation Oncology, CHUOran - Faculty of Medicine, University of Oran, Oran/DZ

Abstract

Introduction

The aim of our study was to analyze the clinical aspects, management and outcomes of rectal cancer in the Algerian west.

Methods

Retrospectively analysed a cohort of 85 patients with rectal cancer (80 primary tumors and 5 local recurrences) who were underwent at the department of radiation oncology of CHUOran between 2008 and 2010.

Results

The mean age was 55.7 ± 3 years (range 17 - 84). Fifty three patients were men and thirty two were women. The tumor sat in an average of 5.1 ± 0.5 cm of the anal margin. 7.1% of patients were stage I, 37.6% stage II, 43.5% stage III and 11.8% stage IV. The major histology type was adenocarcinoma (78.8% of cases). 58 patients received a preoperative radiotherapy with /or without chemotherapy based capecitabine (46 patients); 17 patient a postoperative radiotherapy; 5 patients (local recurrences) neoadjuvant chemotherapy and concomitant chemoradiotherapy and 5 patients a palliative radiotherapy. Only 17 patients received Sphincter preservation (9 in a group of preoperative radiotherapy) In the group of neoadjuvant treatment, the probability of survival after thirty six months follow-up was 42% and the median duration of the survival without relapse was 37.4 + 0.5 months.

Conclusion

The rectal cancer in the Algerian West sees itself at a relatively younger age and locally advanced stage. However, the optimization of their care was necessary to improve the therapeutic results with fewer possible complications connected to treatments (with a high probability of tumor down staging and sphincter preservation).