P-0075 - Endoprosthesis in cardioesophageal junction cancer as a palliative care

Date 28 June 2014
Event World GI 2014
Session Poster Session
Topics Oesophageal Cancer
Palliative Care
Presenter Mansoor Doschanov
Citation Annals of Oncology (2014) 25 (suppl_2): ii14-ii104. 10.1093/annonc/mdu165
Authors M. Doschanov, L. Strutskiy, D. Egamberdiev, K. Qodirov, M. Djuraev
  • National Research Center of Oncology, Tashkent/UZ

Abstract

Introduction

To improve results of treatment and quality of life of patients with unresectable cardioesophageal junction cancer, complicated by stage III-IV dysphagia.

Methods

With the purpose of restoration of patency through the esophagus in clinic of National Research Center of Oncology, jointly with Specialized Research Center of Surgery of Uzbekistan had developed a technique of endoscopic electrocoagulation of cardioesophageal junction tumors with recanalization and endoprosthesis. For this purpose, after usual premedication patients made esophagoscopy and performed coagulation of tumor using an electrode pass over aperture received by biopsy of tumor. To open patency need 3-4 sessions with an interval of 2-3 days. After restoration of patency and recanalization on a configuration of cardioesophageal junction, is made suitable prosthesis from artificial materials, taking account the length of 2 cm above and below from tumoral process, and it placed into with the endoscopic device. An hour after placing of endoprosthesis patients were allowed to eat. The study had been conducted in 56 patients with cardioesophageal junction cancer, complicated by stage III-IV dysphagia. 32 of them men and 24 women.

Results

At 1 of 56 patients noted severe pain after placing prosthesis, that has compelled us to remove it on 3rd day. Other complications associated with endoprosthesis replacement were not observed. Study of the immediate results after 3 weeks and more distant periods showed, that at 3 patients in the lumen of endoprosthesis stuck lump of solid food, which was eliminated after endoscopic sanitation. At 55 (98.2%) of 56 patients results of endoprosthesis replacement for objective and subjective evidences were evaluated for good or excellent, 1 patients' unsatisfactory.

Conclusion

Stage termoelectrocoagulation in unresectable cardioesophageal junction cancer complicated by stage III-IV dysphagia, is the method of choice, which quickly eliminates the phenomenon of dysphagia and improves the quality of patients' life.