P-0192 - Abdominal obesity is associated with the number of colorectal polyps in men but not in women
|Date||28 June 2014|
|Event||World GI 2014|
|Topics|| Cancer Aetiology, Epidemiology, Prevention
|Citation||Annals of Oncology (2014) 25 (suppl_2): ii14-ii104. 10.1093/annonc/mdu165|
Colorectal polyps and excess body weight represent independent risk factors of colorectal cancer. The risk of cancer increases proportionally to the number of colorectal adenomas and the degree of obesity. The aim of this study was to analyze an association between the number of colorectal polyps and presence of abdominal obesity.
The study included 364 individuals (197 women and 167 men) in whom colorectal polyps were detected based on the lower gastrointestinal tract endoscopy and histopathological examination. Depending on a number of the lesions, the participants were divided into two groups: A) with one polyp (n = 177), and B) with at least two polyps (n = 187). Waist circumference was determined in all the subjects, and the results were subjected to statistical analysis.
Abdominal obesity was observed less frequently in persons with one polyp (group A) than in those with at least two polyps (group B) (63.8% vs. 75.4%, p = 0.016). Similar relationship was also documented in men: abnormal waist circumference was determined in 57.1% and 74.2% of male participants from group A and B, respectively (p = 0.021). No such significant difference was documented among women.
This study revealed that abdominal obesity is associated with greater number of colorectal polyps in men but not in women.