297P - Prognosis of epithelial ovarian cancer patients (EOC) with abdominal wall metastasis (AWM) (297P)

Date 18 November 2017
Event ESMO Asia 2017 Congress
Session Poster lunch
Topics Ovarian Cancer
Gynaecologic Malignancies
Presenter Muhammad Muneeb
Citation Annals of Oncology (2017) 28 (suppl_10): x86-x93. 10.1093/annonc/mdx663
Authors T. Mehmood, M. Muneeb
  • Radiation Oncology, Northwest General Hospital and Research Centre, 13014 - Peshawar/PK

Abstract

Background

Patients with the detection of AWM in EOC are categorised as FIGO IVB irrespective of other biologic factors. We evaluated the impact of AWM on patients` overall survival (OS).

Methods

This retrospective study includes 48 patients treated at our institution between 2005 and 2015 and categorized in group A (FIGO IIIC, n = 18), group B (FIGO IV-only AWM, n = 20), and group C (FIGO IV- metastases other than AWM, n = 10). Clinicopathological parameters and survival data were extracted from our prospectively maintained tumor registry. Survival analyses were calculated using Kaplan-Meier method and Cox regression models.

Results

The median overall survival (OS) in group A, B, and C was 37, 58, and 25 months (p 

Conclusions

Prognosis of patients with AWM as the only site of distant metastasis differs significantly from other stage IV-patients. Therefore, up-staging of patients with AWM to FIGO IVB seems not be justified with respect to prognosis. A revision/clarification of the FIGO classification system should be considered to avoid unnecessary stigmatisation as FIGO IVB and to better classify these patients in their respective prognostic group.

Clinical trial identification

Legal entity responsible for the study

Tahir Mehmood

Funding

None

Disclosure

All authors have declared no conflicts of interest.