517P - Primitive neuroectodermal tumor of kidney: analysis of 20 cases

Date 18 December 2016
Event ESMO Asia 2016 Congress
Session Poster lunch
Topics Sarcoma
Presenter Priya Tiwari
Citation Annals of Oncology (2016) 27 (suppl_9): ix163-ix168. 10.1093/annonc/mdw597
Authors P. Tiwari, B. Biswas, S. Bakhshi, L. Kumar
  • Medical Oncology, All India Institute of Medical Sciences, 110029 - New Delhi/IN

Abstract

Background

Primitive neuroectodermal tumor (PNET) of kidneys is a rare entity. Treatment strategies are extrapolation of skeletal PNET. We evaluated clinical characteristics and outcome in 20 patients of renal PNET registered at our centre from January 2005 to December 2015.

Methods

This is a single institutional data review of renal PNET patients. All patients were treated with uniform chemotherapy protocols. Baseline clinical characteristics, histological features, treatment details ad survival outcomes were collected from case files. Overall survival (OS) was calculated from time of diagnosis to death due to any cause.

Results

Median age was 24.5 years (range: 14-67 years). Sixty five percent were males. Most common symptoms were pain abdomen (N = 15, 75%), hematuria (N = 11,55%) and systemic symptoms (N = 6,30%). Anemia (haemoglobin11000cells/μl), hypoalbuminemia (serum albumin

Conclusions

Renal PNET was difficult to identify preoperatively which converted into underutilisation of NACT. A preoperative diagnosis and combined modality treatment is required to improve survival in these patients.

Clinical trial indentification

Not applicable

Legal entity responsible for the study

AIIMS

Funding

AIIMS

Disclosure

All authors have declared no conflicts of interest.