517P - Primitive neuroectodermal tumor of kidney: analysis of 20 cases
|Date||18 December 2016|
|Event||ESMO Asia 2016 Congress|
|Citation||Annals of Oncology (2016) 27 (suppl_9): ix163-ix168. 10.1093/annonc/mdw597|
P. Tiwari, B. Biswas, S. Bakhshi, L. Kumar
Primitive neuroectodermal tumor (PNET) of kidneys is a rare entity. Treatment strategies are extrapolation of skeletal PNET. We evaluated clinical characteristics and outcome in 20 patients of renal PNET registered at our centre from January 2005 to December 2015.
This is a single institutional data review of renal PNET patients. All patients were treated with uniform chemotherapy protocols. Baseline clinical characteristics, histological features, treatment details ad survival outcomes were collected from case files. Overall survival (OS) was calculated from time of diagnosis to death due to any cause.
Median age was 24.5 years (range: 14-67 years). Sixty five percent were males. Most common symptoms were pain abdomen (N = 15, 75%), hematuria (N = 11,55%) and systemic symptoms (N = 6,30%). Anemia (haemoglobin11000cells/μl), hypoalbuminemia (serum albumin
Renal PNET was difficult to identify preoperatively which converted into underutilisation of NACT. A preoperative diagnosis and combined modality treatment is required to improve survival in these patients.
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All authors have declared no conflicts of interest.