210P - Assessment of BMI, lipid profiles, pictogram body size in patients with gastric cancer and its relationship with clinical and pathological stages o...

Date 19 December 2015
Event ESMO Asia 2015 Congress
Session Poster presentation 1
Topics Gastric Cancer
Translational Research
Presenter Reza Zamiri
Citation Annals of Oncology (2015) 26 (suppl_9): 42-70. 10.1093/annonc/mdv523
Authors R.E. Zamiri1, F. Radmand2, Z. Ghadimi3, S. Babaali3, M. Moghimi4
  • 1Oncology, Vali Asr Hospital, 45139-56111 - Zanjan/IR
  • 2General, Vali Asr Hospital, 45139-56111 - Zanjan/IR
  • 3General, Vali Asr Hospital, Zanjan/IR
  • 4Hematology, Vali Asr Hospital, Zanjan/IR

Abstract

Aim/Background

This study aims to find the relationship between pictogram as a symbol for body mass and different types of gastric cancer.

Methods

100 patients with biopsy-proven gastric cancer by endoscopy and 100 healthy people at the beginning of this study were assessed for BMI and pictogram for the age 15 and 30 years. Blood samples of the 100 patients were obtained to evaluate serum lipid levels before starting the treatment. Then, for reassessment of serum lipids, 67 patients were sampled after the treatment period and the results were analyzed using SPSS.

Results

In this study the relationship between risk of gastric cancer in the cardia and non-cardia cases with pictogram at ages 15 and 30 years were not seen. The mean TG level before the treatment was 114 ± 24.7 and after the treatment it was 131 ± 43.9 (P < 0.001), and the mean TC before the treatment was 161 ± 33.9 and after the treatment it was 171 ± 44.71 (P < 0.048). However, both cases indicated a significant increase following the treatment. Mean TG in metastatic patients was 124 ± 33.8 and in patients without metastasis it was 108 ± 22.8 (P < 0.009). 62.1% (52 patients) with gastric cancer showed low HDL serum levels. After the treatment, a significant increase in HDL level was observed in 44 patients (P < 0.02).

Conclusions

Our study did not show a clear and positive association between pictogram at ages of 15 and 30 years old and increased risk of gastric cancer. But it was found that most patients with gastric cancer had low levels of TG, TC and HDL at their referral time. Meanwhile, the increase in HDL level after the treatment may account for gastric cancer as a factor in decreasing HDL level.

Clinical trial identification

Disclosure

All authors have declared no conflicts of interest.