1469P - Survival Patterns for Different Types of Cancers in the United States (1973-2012)

Date 10 September 2017
Event ESMO 2017 Congress
Session Poster display session
Topics Cancer in Adolescents
Bioethics, Legal, and Economic Issues
Cancer Aetiology, Epidemiology, Prevention
Presenter Mohamed Gouda
Citation Annals of Oncology (2017) 28 (suppl_5): v511-v520. 10.1093/annonc/mdx385
Authors M.A. Gouda
  • Department Of Clinical Oncology, Faculty of Medicine - Menoufia University, 32511 - Shebin El Kom/EG

Abstract

Background

Most studies addressing survival patterns focus on 5-years survival data due to difficulties in long-term patients’ follow up. The aim of this study was to explore data on survival making use of the main advantage of SEER (National Cancer Institute Surveillance, Epidemiology, and End Results) program; that is long-term follow up of patients’ records. This enabled reporting 5-years relative survival, 10-years relative survival, and 20-years relative survival for different types of cancers. Survival trends as a function of time and tumor types were also provided.

Methods

SEER*Stat version 8.3.4 was used for data acquisition and analysis, where (SEER 18 Regs Nov 2015 Submission) database was used as the data source. Only cases diagnosed between 1973-2012 with malignant behavior, known age, and microscopic confirmation were included. Relative survival was calculated using Ederer II method. Tumors were classified according to ICD-O-3 into either solid malignancies (8000/3-9581/3) or hematological malignancies (9590/3+).

Results

Cancer cases diagnosed between 1973 and 2012 showed a 5-years relative survival of 64.6% (CI: 64.5%-64.6%), a 10-year relative survival of 58.7% (CI: 58.6%-58.7%), and a 20-years relative survival of 51.4% (CI:51.3%-51.5%). All of these percentages were much higher with solid malignancies than hematological ones [Table].Table:

1469P showing relative survival data as a function of time and tumor type

1973-19821983-19921993-20022003-20121973-2012
All Cases
5-Year RS51%57.8%65.7%68.9%64.6%
10-Year RS43.6%51.1%60.5%63.7%58.7%
20-Year RS36.9%44.4%54.1%51.4%
Solid Malignancies
5-Year RS51.8%58.7%66.6%69.2%65.2%
10-Year RS44.8%52.4%61.8%64.4%59.7%
20-Year RS38.3%46%55.6%52.7%
Hematological Malignancies
5-Year RS42.4%48.4%56.2%65.5%58.1%
10-Year RS30.9%37.5%47.5%56.6%48%
20-Year RS22.7%29.4%38.6%37.9%

Conclusions

Long-term follow up data were suggestive of 20-years relative survival of 51.4% for all cancers. Data were also suggestive of improved relative survival over time. Unexpectedly, hematological malignancies, despite most of them being thought of as curable ones, appeared to have lower relative survival than solid tumors.

Clinical trial identification

N/A

Legal entity responsible for the study

Mohamed Alaa Gouda

Funding

None

Disclosure

All authors have declared no conflicts of interest.