1608P - Bronchoscopic intervention for airway stenosis caused by thyroid tumor

Date 01 October 2012
Event ESMO Congress 2012
Session Poster presentation III
Topics Supportive Care
Presenter Chiyoe Kitagawa
Authors C. Kitagawa1, M. Oki2, Y. Murakami2, K. Hori2, Y. Funahashi2, S. Oka2, R. Tsuboi3, M. Ryuge2, Y. Kogure3, H. Saka3
  • 1Medical Oncology, National Hospital Organization Nagoya Medical Center, 460-0001 - Nagoya/JP
  • 2Department Of Respiratory Medicine, National Hospital Organization Nagoya Medical Center, 460-0001 - Nagoya/JP
  • 3Medical Oncology & Respiratory Medicine, National Hospital Organization Nagoya Medical Center, 460-0001 - Nagoya/JP

Abstract

Background

Although, bronchoscopic intervention has become a widespread way to palliate respiratory symptoms due to airway stenosis, only a few studies have focused on the utility of bronchoscopic treatment for airway stenosis due to thyroid tumor. The aim of this study was to evaluate the efficacy and safety of bronchoscopic intervention in patients with tracheobronchial stenosis due to thyroid tumor.

Methods

We retrospectively investigated patients who underwent bronchoscopic treatment using rigid and flexible bronchoscopes under general anesthesia from July 2000 to December 2011 at Nagoya Medical Center.

Results

During the study period, we performed 428 bronchoscopic interventional procedures for 312 patients. Of the 312 patients, nineteen (7 male, 12 female; median age 77 years [range 52-89]) had airway stenosis due to thyroid tumor (benign in 4, malignant in 15). Fifteen patients underwent stenting (silicone stent placement in 7, self expandable metallic stent placement in 7, silicone stent placement followed by expandable metallic stent placement in 1), and the remaining 4 patients underwent bronchoscopic airway recanalization using argon plasma coagulation, electrocautery or rigid bronchoscopic coring without stenting. Respiratory symptoms improved immediately after the procedure in 15 of 19 patients. The amount of supplemental oxygen could be tapered in all 6 patients who needed supplemental oxygen before the procedure. Acute complications occurred in 4 patients (airway injury during bronchoscopic procedure in 1, stent migration in 1, respiratory failure in 1, and obstruction by secretions in 1). Median survival was 117 days (range 1 – 1951).

Conclusions

Bronchoscopic intervention is an effective and safe treatment for patients with airway stenosis due to thyroid tumor.

Disclosure

All authors have declared no conflicts of interest.