111P - EGFR mutations among lung adenocarcinoma patients in Serbia - EGFR mutation incidence and its correlation with patient demographic characteristics
|Date||28 March 2014|
|Session||Lunch and poster display session|
|Topics|| Non-Small-Cell Lung Cancer, Metastatic
Cancer Aetiology, Epidemiology, Prevention
|Citation||Journal of Thoracic Oncology (2014) 9 (Supplement 9): S7-S52. 10.1097/JTO.0000000000000131|
B. Zaric1, B. Perin2, V. Kovcin3, M. Cekic4, D. Jovanovic5, D. Radosavljevic6, Z. Murtezani7, M. Rancic8, R. Jankovic9, N. Vukobradovic-Djoric10
The detection of EGFR mutations in tumor tissues nowdays is guiding the treatment for advanced NSCLC. It is known that patients with lung adenocarcinoma have more frequent mutations, especially in population of women, non-smokers. The mutation L858R in exon 21 and the deletions in exon 19 account for >85% of all clinically important mutations.