43P - Are tumoural microRNA (miR) a reliable tool in predicting chemosensitivity and prognosis in advanced non-small cell lung cancer (NSCLC)? A prospecti...
|Date||28 March 2014|
|Session||Lunch and poster display session|
|Topics|| Non-Small-Cell Lung Cancer, Metastatic
|Citation||Journal of Thoracic Oncology (2014) 9 (Supplement 9): S7-S52. 10.1097/JTO.0000000000000131|
T. Berghmans1, L. Ameye2, M. Paesmans3, J. Lafitte4, A. Meert5, A. Scherpereel4, I. CsToth5, T. Dernies5, N. Leclercq5, J. Sculier5
The activity of cisplatin chemotherapy for NSCLC is not individually predictable. In a prospective study (Berghmans et al, Lung Cancer 2013), we found two signatures predicting either chemosensitivity (predictive, 2 miR) either survival (prognostic, 4 miR), in a group of 38 patients treated with cisplatin-vinorelbine. We are presenting the results of a validation study.