International Prognostic Index for Agressive Non-Hodgkin's Lymphoma
The International Non-Hodgkin's Lymphoma Prognostic factor Project was undertaken to develop a model for predicting outcomes in patients with aggressive non-Hodgkin's lymphoma on the basis of the patients' clinical characteristics before treatment. Two indexes (the International Prognostic Index and age-adjusted index), were significantly more accurate than the Ann Arbor classification in predicting long-term survival.
Risk factors for the Definition of the International Prognostic Index (IPI)
|General Index||Parameter||Age Adjusted Index|
|1||Age > 60 years||n.a.|
|1||Extra nodal >1 site||non considered|
Risk Groups of the International Prognostic Index
|No. of Risk Factors||No. of Risk Factors||IPI Group|
|0 - 1||0||1 = low|
|2||1||2 = low intermediate|
|3||2||3 = high intermediate|
|4 - 5||3||4 = high|
International Prognostic Index for Aggressive Lymphoma (General IPI)
Age adjusted International prognostic Index
Copyright ©2008 Massachusetts Medical Society. All rights reserved. The International Non-Hodgkin's Lymphoma Prognostic Factors Project. A Predictive Model for Aggressive Non-Hodgkin's Lymphoma.
NEJM 1993, Sept 30, 329(14): 987-994.